Searchable abstracts of presentations at key conferences in endocrinology

ea0081p137 | Environmental Endocrinology | ECE2022

Di-butyl phthalate exposure in a human adrenocortical cell line impairs steroid hormone synthesis

Kallsten Liselott , Pierozan Paula , W Martin Jonathan , Karlsson Oskar

Phthalates are man-made chemicals that are used in many different types of products. The main use is as plasticizers, but they can also be added to, for example, cosmetics, drug coatings, and perfumes. One of the most commonly used phthalates is di-butyl phthalate (DBP), which has been detected in both food and drinking water globally. Once ingested, DBP is rapidly metabolized to its main metabolite, mono-butyl phthalate (MBP), which is frequently detected in human plasma and ...